Betsy Jochum was born in Cincinnati, Ohio, in 1921. She grew up playing ball with neighborhood kids, and was playing in a local women's softball league in 1943 when she was recruited to play in the All American league during its first season. She played until 1948 with the South Bend Blue Sox, and went on the league's spring training trip to Cuba. She later became a physical education teacher, and donated her glove and uniform to the Smithsonian.